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TAS1553
$300 – $2,400
Products Details
Product Description
– TAS1553 is a potent, orally active protein–protein interaction (PPI) inhibitor with an IC50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis. TAS1553 can be used for cancer research[1].
Web ID
– HY-150785
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H20ClFN4O5S
References
– [1]Ueno H, et, al. TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress. Commun Biol. 2022 Jun 9;5(1):571.
CAS Number
– 2166023-31-8
Molecular Weight
– 482.91
Compound Purity
– 99.43
SMILES
– O=C(N)C1=CC(Cl)=CC=C1S(=O)(N[C@H](C(O2)=NNC2=O)[C@@H](C3=C(C)C(C)=CC=C3F)C)=O
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
