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Products Details
Product Description
– TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 62 nM[1].
Web ID
– HY-107997
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C34H40F6N6O4
References
– [1]Yamada K, et al. Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma. J Med Chem. 2017 Oct 26;60(20):8466-8481.
CAS Number
– 1149362-88-8
Molecular Weight
– 710.71
SMILES
– FC(F)(F)C1=CC(CN([C@@H]2C[C@H](CC)N(C(O[C@@H]3CC[C@@H](C(O)=O)CC3)=O)[C@H](CC)C2)C4=NC=C(C5=CN(C)N=C5)C=N4)=CC(C(F)(F)F)=C1
Clinical Information
– Phase 1
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– CETP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
