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Products Details
Product Description
– Tankyrase-IN-4 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 0.8 nM. Tankyrase-IN-4 can be used for the research of cancer[1].
Web ID
– HY-152198
Shipping
– Room temperature
Molecular Formula
– C25H24N6O5
References
– [1]Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.
Molecular Weight
– 488.50
SMILES
– CNC([C@@H](NC(C1=CN=C2C=CC=CC2=C1)=O)CNC(CCN3C(NC(C4=C3C=CC=C4)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PARP
Isoform
– TNKS1/PARP5A
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
