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Products Details
Product Description
– Tamsulosin-d4 (hydrochloride) is deuterium labeled Tamsulosin (hydrochloride). Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models[1].
Web ID
– HY-B0661AS1
Shipping
– Room temperature
Molecular Formula
– C20H25D4ClN2O5S
References
– [1]Christopher Chapple, et al. Tamsulosin: an overview. World J Urol. 2002 Apr;19(6):397-404.|[2]William G. Montgomery, BA, et al. Tamsulosin Attenuates Abdominal Aortic Aneurysm Growth. Surgery. 2018 Nov; 164(5): 1087-1092.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 2518100-55-3
Molecular Weight
– 449.00
SMILES
– O=S(C1=CC(C[C@H](NC([2H])([2H])C([2H])([2H])OC2=CC=CC=C2OCC)C)=CC=C1OC)(N)=O.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Endogenous Metabolite;Isotope-Labeled Compounds
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
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