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TAK1-IN-2
$450 – $4,000
Products Details
Product Description
– TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM[1].
Web ID
– HY-132172
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H26F2N6O5
References
– [1]Veerman JJN, et, al. Discovery of 2,4-1 H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors. ACS Med Chem Lett. 2021 Mar 3;12(4):555-562.
CAS Number
– 2763213-98-3
Molecular Weight
– 540.52
Compound Purity
– 98.22
SMILES
– O=C(C1=CC2=C(CN(C(C3=NC(C(N(CC4=CC=CC=C4OC(F)F)[C@H](C)C(NC)=O)=O)=CN3)=O)C2)C=C1)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– MAP3K
Isoform
– MAP3K7/TAK1
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
