TAK-901

$80$770

Products Details

Product Description

– TAK-901 is a multi-targeted aurora inhibitor with IC50s of 21 and 15 nM for aurora A and B, respectively.

Web ID

– HY-12201

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C28H32N4O3S

References

– [1]Farrell P, et al. Biological characterization of TAK-901, an investigational, novel, multitargeted Aurora B kinase inhibitor. Mol Cancer Ther. 2013 Apr;12(4):460-70.

CAS Number

– 934541-31-8

Molecular Weight

– 504.64

Compound Purity

– 99.84

SMILES

– O=C(NC1CCN(CC1)C)C2=C(C3=C(C4=CC(C)=CN=C4N3)C(C5=CC=CC(S(=O)(CC)=O)=C5)=C2)C

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– DMSO : 2 mg/mL (ultrasonic;warming)

Target

– Aurora Kinase

Isoform

– Aurora A;Aurora B

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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