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Products Details
Product Description
– TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].
Web ID
– HY-114234A
Shipping
– Room temperature
Molecular Formula
– C27H31NO
References
– [1]Fukumoto H, et al. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer’s disease. J Neurosci. 2010 Aug 18;30(33):11157-66.
CAS Number
– 212571-56-7
Molecular Weight
– 385.54
SMILES
– CN(CC[C@H]1CC2=C(CC1)C=C(C=C2)OCC3=CC=C(C=C3)C4=CC=CC=C4)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Beta-secretase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
