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Products Details
Product Description
– TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1].
Web ID
– HY-105168
Shipping
– Room temperature
Molecular Formula
– C45H51N9Na2O11S
References
– [1]Toshifumi Watanabe, et al. TAK-044: An Endothelin Receptor Antagonist. , 14(1), 36–46.
CAS Number
– 157380-72-8
Molecular Weight
– 971.98
SMILES
– O=C([C@@H](NC([C@H](C1=CC=CS1)NC([C@@H](NC([C@@H](NC([C@H](NC2=O)CC(O[Na])=O)=O)CC(N3CCN(C4=CC=CC=C4)CC3)=O)=O)CC(O[Na])=O)=O)=O)CC(C)C)N[C@@H]2CC5=CNC6=CC=CC=C56
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Endothelin Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
