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Products Details
Product Description
– TACC3 inhibitor 1 is a potent and cross the blood-brain barrier TACC3 inhibitor. TACC3 inhibitor 1 induces Apoptosis and cell cycle arrest at G2/M phase. TACC3 inhibitor 1 induces the generation of intracellular ROS. TACC3 inhibitor 1 shows antiproliferative and anti-tumor activity[1].
Web ID
– HY-151985
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H21N5OS
References
– [1]Zhao W, et al. Discovery of novel analogs of KHS101 as transforming acidic coiled coil containing protein 3 (TACC3) inhibitors for the treatment of glioblastoma. Eur J Med Chem. 2022 Dec 15;244:114874.
Molecular Weight
– 379.48
SMILES
– OC1CC2CC1CN2C3=CC=NC(NCC4=CSC(C5=CC=CC=C5)=N4)=N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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