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T-1-MCPAB
Products Details
Product Description
– T-1-MCPAB is a VEGFR-2 inhibitor (IC50=0.135 µM) that effectively inhibits MCF7 migration. T-1-MCPAB can be used in cancer research[1].
Web ID
– HY-156452
Shipping
– Room temperature
Molecular Formula
– C22H19ClN6O4
References
– [1]Eissa IH, et al. Anti-breast cancer potential of a new xanthine derivative: In silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies. Pathol Res Pract. 2023 Nov;251:154894.
Molecular Weight
– 466.88
SMILES
– CN(C(N1CC(NC2=CC=C(C(NC3=CC=CC(Cl)=C3)=O)C=C2)=O)=O)C(N=CN4C)=C4C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.