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Products Details
Product Description
– SZ-015268 is a CDK7 inhibitor with an IC50 of 23.56 nM. SZ-015268 has extremely significant anti-tumor advantages. SZ-015268 inhibits HCC70, OVCAR-3, HCT116 and HCC1806 cells proliferation with IC50s of 33, 80.56, 12.53, and 61.55 nM, respectively[1].
Web ID
– HY-145389
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H38N8O3
References
– [1]Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof. WO2021121390A1.
CAS Number
– 2654003-68-4
Molecular Weight
– 498.62
SMILES
– CC(C1=CN=C(C(NC(CC2)CCN2C(O[C@@H](CC3)CN3C(/C=C/CN(C)C)=O)=O)=N4)N1N=C4C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK7
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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