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Synstab A
SKU
HY-116915-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Cytoskeleton, Microtubule/Tubulin
Products Details
Product Description
– Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].
Web ID
– HY-116915
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H13BrCl3N3O3S
References
– [1]Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378.|[2]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.
CAS Number
– 257612-36-5
Molecular Weight
– 501.61
SMILES
– O=C(C1=CC=C(C=C1)Br)NC(C(Cl)(Cl)Cl)NC2=CC=C(C=C2)S(=O)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.