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Products Details
Product Description
– Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].
Web ID
– HY-116915
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H13BrCl3N3O3S
References
– [1]Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378.|[2]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.
CAS Number
– 257612-36-5
Molecular Weight
– 501.61
SMILES
– O=C(C1=CC=C(C=C1)Br)NC(C(Cl)(Cl)Cl)NC2=CC=C(C=C2)S(=O)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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