Products Details

Product Description

– Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].

Web ID

– HY-116915

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C15H13BrCl3N3O3S

References

– [1]Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378.|[2]Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.

CAS Number

– 257612-36-5

Molecular Weight

– 501.61

SMILES

– O=C(C1=CC=C(C=C1)Br)NC(C(Cl)(Cl)Cl)NC2=CC=C(C=C2)S(=O)(N)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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