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SYK/JAK-IN-1
SKU
HY-145029-Get quote
Category Reference compound
Tags Cancer; Inflammation/Immunology, Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt, JAK;Syk
Products Details
Product Description
– SYK/JAK-IN-1 is dual SYK/JAK inhibitor with IC50s of <5 nM for SYK and JAK2, respectively[1].
Web ID
– HY-145029
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H26N8O3
References
– [1]Compound containing fused tricyclic structure. WO2021219100A1.
CAS Number
– 2737326-28-0
Molecular Weight
– 474.52
SMILES
– N#CCC(CC1)CCN1C2=NC(NC3=CC=C(N4[C@](COCC4)([H])CO5)C5=C3)=C6C(C=NNC6=O)=N2
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– JAK;Syk
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.