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Products Details
Product Description
– Syk-IN-3, a potent spleen tyrosine kinase (Syk) inhibitor, extracted from patent WO2011075515A1, compound example 152, has an IC50 of 1 nM[1].
Web ID
– HY-130680
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H28N4O3S
References
– [1]Muller S, et al. Donated chemical probes for open science.CITEÂ THIS ARTICLEAS:Â eLife 2018;7:e34311.
CAS Number
– 1312534-69-2
Molecular Weight
– 452.57
SMILES
– O=C([C@@H]1C(C)(C)C[C@](C2=NC=C(C3=CC(NC4=NC=CC(C)=N4)=CC(C)=C3)S2)(O)CC1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Syk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
