Syk-IN-1

$500$4,600

Products Details

Product Description

– Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].

Web ID

– HY-12657

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H22N8O

References

– [1]Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25(20):4642-4647.

CAS Number

– 1491150-77-6

Molecular Weight

– 366.42

Compound Purity

– 99.18

SMILES

– NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Syk

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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