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Syk-IN-1
SKU
HY-12657-10 mg
Category Reference compound
Tags Inflammation/Immunology, Protein Tyrosine Kinase/RTK, Syk
$500 – $4,600
Products Details
Product Description
– Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM[1].
Web ID
– HY-12657
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H22N8O
References
– [1]Thoma G, et al. Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg Med Chem Lett. 2015;25(20):4642-4647.
CAS Number
– 1491150-77-6
Molecular Weight
– 366.42
Compound Purity
– 99.18
SMILES
– NC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Syk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.