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Products Details
Product Description
– Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].
Web ID
– HY-B1787
Shipping
– Room temperature
Molecular Formula
– C20H17FO4S
References
– [1]Aono Y, et al. Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210.
CAS Number
– 59973-80-7
Molecular Weight
– 372.41
SMILES
– O=C(O)CC(C1=C/2C=CC(F)=C1)=C(C)C2=CC3=CC=C(S(=O)(C)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
