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Products Details
Product Description
– Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].
Web ID
– HY-B1787
Shipping
– Room temperature
Molecular Formula
– C20H17FO4S
References
– [1]Aono Y, et al. Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210.
CAS Number
– 59973-80-7
Molecular Weight
– 372.41
SMILES
– O=C(O)CC(C1=C/2C=CC(F)=C1)=C(C)C2=CC3=CC=C(S(=O)(C)=O)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
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