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Product Description
– Sulbactam-d2 (sodium) is the deuterium labeled Sulbactam sodium[1]. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus–Acinetobacter baumannii (Acb) complex[2][3].
Web ID
– HY-B0334AS1
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H8D2NNaO5S
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Noguchi JK, et al. Sulbactam: a beta-lactamase inhibitor. Clin Pharm. 1988;7(1):37-51.|[3]Lin HS, et al. Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Infect Dis (Lond). 201547(6):370-378.|[4]Betrosian AP, et al. Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections. Expert Opin Drug Metab Toxicol. 20095(9):1099-1112.
CAS Number
– 948027-82-5
Molecular Weight
– 257.24
SMILES
– O=C([C@@H]1N2[C@](C([2H])([2H])C2=O)([H])S(=O)(C1(C)C)=O)O[Na]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Isotope-Labeled Compounds
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