Download Files:
SUCNR1-IN-1
$370 – $3,140
Products Details
Product Description
– SUCNR1-IN-1 (Compound 20) is a SUCNR1 inhibitor (IC50: 88 nM for hSUCNR1). SUCNR1-IN-1 can be used for research of rheumatoid arthritis, liver fibrosis, or obesity[1].
Web ID
– HY-154946
Shipping
– Room temperature
Molecular Formula
– C26H22ClF3N2O4
References
– [1]Velcicky J, et al. Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. J Med Chem. 2020 Sep 10;63(17):9856-9875.
CAS Number
– 2711753-52-3
Molecular Weight
– 518.91
SMILES
– FC1=CC(Cl)=C(O[C@@H]2CCCNC2)C=C1C3=C(C(C(NC4=C(C=C(C=C4)F)CC(O)=O)=O)=CC=C3)F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Succinate Receptor 1
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
