Products Details

Product Description

– STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell[1].

Web ID

– HY-148645

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C17H18N8O

References

– [1]Ketan Satish GAJIWALA, et al. Modulators of sting (stimulator of interferon genes). WO2022195462A1.

CAS Number

– 2839639-72-2

Molecular Weight

– 350.38

SMILES

– O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– STING

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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