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Products Details
Product Description
– STING-IN-4 (Compound 1) is a STING inhibitor that inhibits STING expression and hence reducing activation of STING and nuclear factor-κB (NF-κB) signaling. STING-IN-4 shows anti-inflammatory activity and can be used for the research of sepsis[1].
Web ID
– HY-151970
Shipping
– Room temperature
Molecular Formula
– C32H46N2O3
References
– [1]Yu T, et al. Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114911.
CAS Number
– 2250374-27-5
Molecular Weight
– 506.72
SMILES
– CC1(CC[C@@]2(CC[C@@]3(C(C2C1)=CCC4[C@]5(CC6=C([C@@](CO)(C5CC[C@]43C)C)N=CC=N6)C)C)C(O)=O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
