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STING agonist-8
SKU
HY-144168-Get quote
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, STING
Products Details
Product Description
– STING agonist-8 is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells (WO2021239068A1, compound 5-AB)[1].
Web ID
– HY-144168
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C41H46N14O4
References
– [1]Heterocyclic compounds as sting modulators. WO2021239068A1.
CAS Number
– 2745723-90-2
Molecular Weight
– 798.90
SMILES
– O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCC6CNC6)C=C(C(N)=O)C=C5C7=CN=C(C8=CC(C)=NN8CC)N=C74
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.