STING agonist-4

SKU HY-123943-1 mg Category Tags , ,

$200$2,520

Products Details

Product Description

– STING agonist-4 is an stimulator of Interferon Genes (STING) receptor agonist with an apparent inhibitory constant (IC50) of 20 nM. STING agonist-4 is a two symmetry-related amidobenzimidazole (ABZI)-based compound to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function[1].

Web ID

– HY-123943

Storage Temperature

– -20°C (Powder, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-Kinase/protease

Molecular Formula

– C34H38N12O4

References

– [1]Ramanjulu JM et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Dec;564(7736):439-443.

CAS Number

– 2138300-40-8

Molecular Weight

– 678.74

Compound Purity

– 99.52

SMILES

– O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC(C)=NN6CC)=O)=NC2=C1)N

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 10 mg/mL (ultrasonic)

Target

– STING

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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