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STING agonist-4
$200 – $2,520
Products Details
Product Description
– STING agonist-4 is an stimulator of Interferon Genes (STING) receptor agonist with an apparent inhibitory constant (IC50) of 20 nM. STING agonist-4 is a two symmetry-related amidobenzimidazole (ABZI)-based compound to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function[1].
Web ID
– HY-123943
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C34H38N12O4
References
– [1]Ramanjulu JM et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Dec;564(7736):439-443.
CAS Number
– 2138300-40-8
Molecular Weight
– 678.74
Compound Purity
– 99.52
SMILES
– O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC(C)=NN6CC)=O)=NC2=C1)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic)
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.