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STING agonist-31
Products Details
Product Description
– STING agonist-31 is a STING agonist, with EC50 values of 0.24 and 39.51 μM for h-STING and m-STING. STING agonist-31 has antitumor efficiency[1].
Web ID
– HY-153546
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C43H51N15O6
References
– [1]Song Z, et al. Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists. J Med Chem. 2021 Feb 11;64(3):1649-1669.
CAS Number
– 2719001-44-0
Molecular Weight
– 873.96
SMILES
– O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OCCCN4CCOCC4)=C3N2C/C=C/CN5C6=C(OC)C=C(C7=NN=CN7)C=C6N=C5NC(C8=CC(C)=NN8CC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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