Download Files:
STING agonist-12
SKU
HY-147010-10 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, STING
$100 – $810
Products Details
Product Description
– STING agonist-12 (Compound 53) is a potent, orally active human STING activator with an EC50 of 185 nM[1].
Web ID
– HY-147010
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H19ClF4N2O2
References
– [1]Pryde DC, et al. The discovery of potent small molecule activators of human STING. Eur J Med Chem. 2021 Jan 1;209:112869.
CAS Number
– 2259624-71-8
Molecular Weight
– 490.88
Compound Purity
– 98.63
SMILES
– ClC1=CC=CC(F)=C1CN2C3=C(C(C)(C2=O)C)C=CC(C(NCC4=C(C=C(C=C4F)F)F)=O)=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.