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Products Details
Product Description
– Stigmane B (Compound 2) is a nuclear factor E2-related factor (Nrf2) activator. Stigmane B downregulates apoptosis and reactive oxygen species (ROS) generation, and increases antioxidant enzyme activities. Stigmane B shows neuroprotective effects[1].
Web ID
– HY-N10431
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H30O4
References
– [1]Song XY, et al. Terpenoids from stigma maydis (Zea mays L.) alleviate hydrogen peroxide-induced SH-SY5Y cell injury by activating Nrf2. Bioorg Chem. 2020 Sep;102:104131.
Molecular Weight
– 346.46
SMILES
– COC([C@@]1(CCC[C@]2([C@H]3[C@@]4(CC[C@]12[H])C[C@H](C(C(O)=O)=C4)CC3)C)C)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Keap1-Nrf2
Pathway
– NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
