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Products Details
Product Description
– STC314 is a small polyanion that interact electrostatically with histones. STC314 blocks disruption of lipid-bilayers by histones that inhibits the cytotoxic, platelet-activating and erythrocyte-damaging effects of histones. STC314 has anti-infective effects and can be uesd for sepsis research[1].
Web ID
– HY-145996
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H17Na7O32S7
References
– [1]Connor H O’ Meara, et al. Neutralizing the pathological effects of extracellular histones with small polyanions. Nat Commun. 2020 Dec 16;11(1):6408.
CAS Number
– 186295-19-2
Molecular Weight
– 1070.64
SMILES
– O=[S](O[C@H]([C@H]1O[S](=O)(O[Na])=O)[C@@H]([C@H](O[C@H]1OC)CO[S](=O)(O[Na])=O)O[C@H](O[C@@H]2CO[S](=O)(O[Na])=O)[C@@H]([C@H]([C@H]2O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)O[S](=O)(O[Na])=O)(O[Na])=O
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
