Products Details

Product Description

– STAT3-IN-5 is a potent STAT3 inhibitor. STAT3-IN-5 inhibits STAT3-Y705 phosphorylation with an EC50 value of 170 nM. STAT3-IN-5 inhibits cytokine induced JAK activation. STAT3-IN-5 induces apoptosis. STAT3-IN-5 can be used in research of cancer[1].

Web ID

– HY-112447

Shipping

– Room temperature

Molecular Formula

– C19H7F7N2O3

References

– [1]Xu J, et, al. Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid esters. J Med Chem. 2008 Jul 24;51(14):4115-21.

CAS Number

– 1041438-68-9

Molecular Weight

– 444.26

SMILES

– N#CC1=C(C(F)=C(N2C=C(C(C3=CC(F)=C(C(F)=C32)F)=O)C(OCC)=O)C(F)=C1F)F

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– STAT

Isoform

– STAT3

Pathway

– JAK/STAT Signaling;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=