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STAT3 degrader-1
SKU
HY-147048-Get quote
Category Reference compound
Tags Cancer, JAK/STAT Signaling;Stem Cell/Wnt, STAT
Products Details
Product Description
– STAT3 degrader-1 (compound 295) is a potent STAT3 degrader. STAT3 degrader-1 can be used for researching anticancer[1]. STAT3 degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-147048
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C58H63F5N9O12PS
References
– [1]Shaomeng Wang. Small molecule degraders of stat3. WO2020198435A1 (compound 295)
CAS Number
– 2497585-16-5
Molecular Weight
– 1236.20
SMILES
– FC(C=C1)=CC=C1C[C@H](NC([C@H](CCC(N)=O)NC([C@H]2N3[C@](CCN(C[C@@H](C3=O)NC(C4=CC5=CC(C(F)(F)P(O)(O)=O)=CC=C5S4)=O)CC(F)F)([H])CC2)=O)=O)C(N(CC6)CCC6CCC#CC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=CC=C7)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– STAT
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.