Products Details

Product Description

– STAT3 degrader-1 (compound 295) is a potent STAT3 degrader. STAT3 degrader-1 can be used for researching anticancer[1]. STAT3 degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Web ID

– HY-147048

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C58H63F5N9O12PS

References

– [1]Shaomeng Wang. Small molecule degraders of stat3. WO2020198435A1 (compound 295)

CAS Number

– 2497585-16-5

Molecular Weight

– 1236.20

SMILES

– FC(C=C1)=CC=C1C[C@H](NC([C@H](CCC(N)=O)NC([C@H]2N3[C@](CCN(C[C@@H](C3=O)NC(C4=CC5=CC(C(F)(F)P(O)(O)=O)=CC=C5S4)=O)CC(F)F)([H])CC2)=O)=O)C(N(CC6)CCC6CCC#CC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=CC=C7)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– STAT

Pathway

– JAK/STAT Signaling;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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