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SSR504734
SKU
HY-10715-10 mg
Category Reference compound
Tags GlyT, Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
$600 – $5,800
Products Details
Product Description
– SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities[1].
Web ID
– HY-10715
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H21Cl2F3N2O
References
– [1]Ronan Depoortère, et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology. 2005 Nov;30(11):1963-85.
CAS Number
– 615571-23-8
Molecular Weight
– 433.29
Compound Purity
– 99.82
SMILES
– O=C(C1=C(C(C(F)(F)F)=CC=C1)Cl)N[C@H]([C@]2([H])CCCCN2)C3=CC=CC=C3.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– GlyT
Isoform
– GlyT1
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.