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Products Details
Product Description
– SRTCX1002 is a potent activator of SIRT1 (STAC), suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB Activity. SRTCX1002 suppresses stimuli-induced NF-κB transcriptional activation and LPS-induced TNFα secretion with IC50s of 0.71 and 7.58 µM, respectively[1].
Web ID
– HY-114981
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H19N5O2S
References
– [1]Hongying Yang, et al. SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. PLoS One. 2012;7(9):e46364.
CAS Number
– 1203479-63-3
Molecular Weight
– 405.47
SMILES
– O=C(NC1=NC=CS1)C2=C3NC(C4=CC=CC(N5CCOCC5)=C4)=NC3=CC=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
