(S,R,S)-AHPC-PEG5-Boc

$560$950

Products Details

Product Description

– (S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V[1].

Web ID

– HY-131959

Storage Temperature

– -20°C (Powder, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C40H62N4O11S

References

– [1]Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

CAS Number

– 2923734-82-9

Molecular Weight

– 807.01

Compound Purity

– 95.29

SMILES

– CC(C)(C)[C@@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)NC(CCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– E3 Ligase Ligand-Linker Conjugates

Isoform

– von Hippel-Lindau (VHL)

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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