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(S,R,S)-AHPC-amido-C7-acid
SKU
HY-148671-100 mg
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
$190 – $480
Products Details
Product Description
– (S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design PROTACs[1].
Web ID
– HY-148671
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C31H44N4O6S
References
– [1]Sun N, et al. Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer. J Med Chem. 2023 Jan 12;66(1):596-610.
CAS Number
– 2172819-76-8
Molecular Weight
– 600.77
Compound Purity
– 98.28
SMILES
– OC(CCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.