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SR 49059
$185 – $2,000
Products Details
Product Description
– SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a Ki vaule of 1.4 nM[1].
Web ID
– HY-18345
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C28H27Cl2N3O7S
References
– [1]Serradeil-Le Gal C, et al. Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells. Am J Physiol. 1995 Jan;268(1 Pt 2):H404-10.|[2]Shuaib A, et al. Effects of nonpeptide V(1) vasopressin receptor antagonist SR-49059 on infarction volume and recovery of function in a focal embolic stroke model. Stroke. 2002 Dec;33(12):3033-7.
CAS Number
– 150375-75-0
Molecular Weight
– 620.50
Compound Purity
– 99.92
SMILES
– ClC1=C([C@@]2(O)C3=CC(Cl)=CC=C3N(S(=O)(C4=CC(OC)=C(OC)C=C4)=O)[C@]2(C(N5[C@H](C(N)=O)CCC5)=O)[H])C=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Vasopressin Receptor
Isoform
– V1a ReceptorÂ
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
