Download Files:
SR-3737
SKU
HY-117248-Get quote
Category Reference compound
Tags JNK;p38 MAPK, MAPK/ERK Pathway, Neurological Disease
Products Details
Product Description
– SR-3737 is a JNK3 and p38 inhibitor (IC50: 12 and 3 nM)[1].
Web ID
– HY-117248
Shipping
– Room temperature
Molecular Formula
– C29H25FN4O4
References
– [1]Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284(19):12853-61.
CAS Number
– 1164153-37-0
Molecular Weight
– 512.53
SMILES
– O=C(NC1=CC(OC)=C(OC)C(OC)=C1)C2=CC=CC(N3N=CC4=C3C=CC(NC5=CC=CC=C5F)=C4)=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– JNK;p38 MAPK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.