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Products Details
Product Description
– SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites[1].
Web ID
– HY-112247
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C17H12ClN3O4
References
– [1]Brust R, et al. Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. ACS Chem Biol. 2017 Apr 21;12(4):969-978.
CAS Number
– 2088135-12-8
Molecular Weight
– 357.75
SMILES
– O=C(NC1=CC=NC2=CC=C(OC)C=C12)C3=CC([N+]([O-])=O)=CC=C3Cl
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– PPAR
Isoform
– PPARγ
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
