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Products Details
Product Description
– SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a Ki of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC50 of 1.65 μM[1].
Web ID
– HY-150506
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C30H32ClN3O3
References
– [1]Santo Previti, et al. Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain. ACS Med. Chem. Lett. 2022
Molecular Weight
– 518.05
SMILES
– O=C(C)/C=C/[C@@H](NC([C@@H](NC(NC(C(C)=C1)=CC=C1Cl)=O)CC2=CC=CC=C2)=O)CCC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
