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Products Details
Product Description
– SphK1-IN-3 is an effective sphingosine kinase-1 (SphK1) inhibitor. SphK1-IN-3 inhibits SphK1 kinase activity with an IC50 value of 2.48 μM. SphK1-IN-3 can be used for the research of many diseases such as cancer, rheumatoid arthritis, diabetes, asthma, and pulmonary fibrosis[1].
Web ID
– HY-148262
Shipping
– Room temperature
Molecular Formula
– C21H20N6O3
References
– [1]Shadia A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. Med Chem Res 30, 1614–1634 (2021).
Molecular Weight
– 404.42
SMILES
– O=[N+](C1=CC=C2NC(C3=C(N4CCOCC4)N(C5=CC=CC=C5)N=C3C)=NC2=C1)[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SphK
Isoform
– SphK1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
