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SPHINX
$280 – $1,950
Products Details
Product Description
– SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD[1].
Web ID
– HY-132126
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H17F3N2O3
References
– [1]Gammons MV, et al. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6052-62.
CAS Number
– 848057-98-7
Molecular Weight
– 354.32
Compound Purity
– 99.87
SMILES
– O=C(C1=CC=C(C)O1)NC2=CC(C(F)(F)F)=CC=C2N3CCOCC3
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– SRPK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.