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SP-2-225
SKU
HY-155176-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Epigenetics, HDAC
Products Details
Product Description
– SP-2-225 is a selective HDAC6 inhibitor. SP-2-225 enhance the production of cancer-associated antigens and macrophage antigen cross-presentation to T cells. SP-2-225 reduces the tumor volume in a syngeneic SM1 melanoma model[1].
Web ID
– HY-155176
Shipping
– Room temperature
Molecular Formula
– C28H34N2O3
References
– [1]Scott Grindrod, et al. Abstract PO023: Immune-mediated tumor growth inhibition by selective HDAC6 inhibitor SP-2-225. Cancer Immunol Res (2021) 9 (2_Supplement): PO023.
CAS Number
– 2364448-93-9
Molecular Weight
– 446.58
SMILES
– CC1=C(COC2=CC=C(CNCCCCCC(NO)=O)C=C2C)C=CC=C1C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.