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Sotorasib (racemate)
$63 – $605
Products Details
Product Description
– Sotorasib (AMG-510) racemate is the racemate of Sotorasib (AMG-510). AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
Web ID
– HY-114277A
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H30F2N6O3
References
– [1]Karen Rex, et al. Abstract 3090: In vivo characterization of AMG 510 – a potent and selective KRASG12Ccovalent small molecule inhibitor in preclinical KRASG12Ccancer models. Experimental and Molecular Therapeutics.
CAS Number
– 2252403-56-6
Molecular Weight
– 560.59
Compound Purity
– 98.99
SMILES
– O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[C@@H](C)CN(C(C=C)=O)CC5)=N1
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 3.85 mg/mL (ultrasonic)
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
