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Products Details
Product Description
– SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1].
Web ID
– HY-144211
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H25F3N4O3
References
– [1]Pyridine-pyrimidine derivative, preparation method therefor and pharmaceutical use thereof. WO2021249519A1.
CAS Number
– 2755415-30-4
Molecular Weight
– 462.46
SMILES
– C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC2=C3C(NC(C)=N2)=NC(C([C@@]4(CC[C@H](CC4)O)O)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
