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Products Details
Product Description
– SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1].
Web ID
– HY-145048
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H31F3N4O5
References
– [1]Xin Li, et al. Pyrimidobicyclic derivatives, their preparation method and their application in medicine. Patent WO2021203768A1.
CAS Number
– 2716956-47-5
Molecular Weight
– 536.54
SMILES
– C[C@H](C1=CC(C(F)(F)F)=CC(N)=C1)NC2=NC(C)=NC3=C2C=C(OCCOCCOCCOCCO4)C4=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
