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SOS1-IN-3
Products Details
Product Description
– SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1)[1].
Web ID
– HY-145046
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H21F3N4O
References
– [1]Juergen Ramharter, et al. Novel benzylamino substituted pyridopyrimidinones and derivatives as sos1 inhibitors. WO2019122129A1
CAS Number
– 2359689-76-0
Molecular Weight
– 402.41
SMILES
– C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC(C2=CN3C4(CC4)C)=NC(C)=NC2=CC3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
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