Download Files:
Products Details
Product Description
– SOS1-IN-10 is a potent SOS1 inhibitor with an IC50 of 13 nM for KRAS G12C-SOS1 (WO2022017519A1, compound 8)[1].
Web ID
– HY-144213
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H19F5N4O
References
– [1]Quinazoline compound. WO2022017519A1.
CAS Number
– 2758690-15-0
Molecular Weight
– 450.40
SMILES
– C=C[C@H](C1=CC=CC(C(F)F)=C1F)NC2=NC(C)=NC3=CC(N(C=C32)C4(CC4)C(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
