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Products Details
Product Description
– Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease[1].
Web ID
– HY-148650
Shipping
– Room temperature
Molecular Formula
– C20H24N2O4
References
– [1]Kjoelby, Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss. WO2022074119. 2022.
CAS Number
– 2691846-93-0
Molecular Weight
– 356.42
SMILES
– CC(C)(C)CC[C@@H](C(O)=O)NC(C(C=N1)=CC=C1OC2=CC=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neurotensin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
