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Products Details
Product Description
– SMS2-IN-3 is a potent and selective SMS2inhibitor (IC50=2.2 nM), significantly reduces the hepatic SM (22:0) levels[1].
Web ID
– HY-150559
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C33H39F3N4O6
References
– [1]Takafumi Yukawa, et al. Discovery of 1,8-naphthyridin-2-one derivative as a potent and selective sphingomyelin synthase 2 inhibitor. Bioorg Med Chem. 2020 Apr 1;28(7):115376.
CAS Number
– 2414240-89-2
Molecular Weight
– 644.68
SMILES
– O=C(N1CCC(CCCOC(C2=C(N3C)N=CC=C2)=C(C(N(CC4=CC(OC)=CC(C(F)(F)F)=C4)C)=O)C3=O)CC1)OC5(CC5)C
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Others
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
