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SM-433 (hydrochloride)
$220 – $4,900
Products Details
Product Description
– SM-433 hydrochlorid, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 hydrochlorid exhibits strong binding affinity XIAP BIR3 protein with an IC50<1 μM (patent WO2008128171A2)[1].
Web ID
– HY-138059A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H44ClN5O4
References
– [1]Shaomeng Wang, et al. Diazo bicyclic smac mimetics and the uses thereof. WO2008128171A2.
Molecular Weight
– 598.18
Compound Purity
– 98.57
SMILES
– O=C([C@@H]1CC[C@@](CCN(C(CC(C)C)=O)C[C@@H]2NC([C@@H](NC)C)=O)([H])N1C2=O)NCC3=CC=CC=C3C4=CC=CC=C4.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 180 mg/mL (ultrasonic)|H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;IAP
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
