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Products Details
Product Description
– Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
Web ID
– HY-N1235
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H14O6
References
– [1]Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570.|[2]Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.
CAS Number
– 41060-16-6
Molecular Weight
– 314.29
SMILES
– O=C1C=C(C2=CC=CC=C2O)OC3=C(OC)C(OC)=CC(O)=C13
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Elastase;MicroRNA
Pathway
– Epigenetics;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
