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Skullcapflavone I

Products Details

Product Description

– Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].

Web ID

– HY-N1235

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C17H14O6

References

– [1]Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570.|[2]Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830.

CAS Number

– 41060-16-6

Molecular Weight

– 314.29

SMILES

– O=C1C=C(C2=CC=CC=C2O)OC3=C(OC)C(OC)=CC(O)=C13

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Elastase;MicroRNA

Pathway

– Epigenetics;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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