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SKF 91488 (dihydrochloride)

Products Details

Product Description

– SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a Ki value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice[1].

Web ID

– HY-100967

Shipping

– Room temperature

Molecular Formula

– C7H19Cl2N3S

References

– [1]Beaven MA, et, al. Inhibition of histamine methylation in vivo by the dimaprit analog, SKF Compound 91488. Agents Actions. 1979 Dec;9(5-6):455-60.

CAS Number

– 68941-21-9

Molecular Weight

– 248.22

SMILES

– N=C(N)SCCCCN(C)C.Cl.Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Histone Methyltransferase

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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