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SKF 81297 (hydrobromide)
SKU
HY-12236-10 mg
Category Reference compound
Tags Dopamine Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
$220 – $350
Products Details
Product Description
– SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].
Web ID
– HY-12236
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H17BrClNO2
References
– [1]Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7.|[2]Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.
CAS Number
– 67287-39-2
Molecular Weight
– 370.67
Compound Purity
– 99.0
SMILES
– OC1=CC2=C(C(Cl)=C1O)CCNCC2C3=CC=CC=C3.Br
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMF : ≥ 20 mg/mL|DMSO : ≥ 20 mg/mL|Ethanol : ≥ 2 mg/mL
Target
– Dopamine Receptor
Isoform
– D1 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.